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Products for use in the clinical diagnosis of viral infections, including SARS-CoV-2, the virus that causes COVID-19, by simultaneously measuring multiple analytes from a single sample.
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The Mesoscale K15616U-2 is a high-performance thermoelectric cooler that provides precise temperature control for photonics and semiconductor applications It features a maximum heat pumping capacity of 15 6W and can achieve a maximum temperature differential of 68 C The K15616U-2 has a low profile compact design with dimensions of 40 x 40 x 3 4mm It requires an input voltage of 2 2V and can draw up to 6 8A of current The operating temperature range is -20 C to 80 C Key features include low thermal resistance high stability and quiet operation With robust construction the K15616U-2 provides reliable maintenance-free cooling for sensitive components and instruments
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The Meso Scale Discovery SARS-CoV-2 S1 RBD N501Y Protein is a recombinant protein corresponding to the receptor binding domain (RBD) of the SARS-CoV-2 spike protein with the N501Y mutation This protein can be used in immunoassays and as an immunogen The molecular weight is 25 8 kDa This product is supplied lyophilized from a 0 2 m filtered solution in PBS The recommended storage is at -20 C The protein is produced in HEK293 cells
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The Meso Scale Discovery K15653U-4 is a 96-well plate with a carbon electrode sensor for label-free detection of proteins via electrochemiluminescence (ECL) It offers high-sensitivity quantitative analysis and screening with low background and high signal-to-noise ratios The product includes 4 plates each allowing 96 assays Compatible with Meso Scale Discovery instruments and reagents it supports ECL-based immunoassays biomolecular interaction analysis and cell signaling studies featuring high sensitivity broad dynamic range and rapid assay times
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The Mesoscale K15691U-4 is a 4-channel 16-bit 250 kS/s simultaneous sampling data acquisition module It has 4 analog voltage input channels with programmable gain amplifiers anti-aliasing filters and 16-bit ADCs The input voltage range is 10 V with software-selectable gains of 1 2 4 8 It has a USB interface and is compatible with Windows Linux and Mac operating systems The module is bus-powered and compact in size Key features include 250 kS/s sampling rate 16-bit resolution 10 V input range programmable gains anti-aliasing filters USB interface and cross-platform software support
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The Meso Scale Discovery V-PLEX Metabolic Panel 1 Human Kit quantifies insulin leptin resistin PAI-1 total and MCP-1 in human serum plasma and cell culture supernatants This electrochemiluminescent multiplex assay uses MSD s V-PLEX technology for sensitive reproducible results with low sample volume The kit includes a 96-well plate with capture antibodies detection antibodies calibrators and controls for standard curves and assay validation It offers a streamlined workflow for analyzing metabolic biomarkers related to obesity diabetes and cardiovascular disease
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A polyphenol flavonoid reduces iron- and ascorbate-induced lipid peroxidation of isolated bovine brain phospholipid liposomes (IC50 20 UM) inhibits HCV RdRp by 17 7 in an enzyme assay
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An alkaloid active against the F32 chloroquine-sensitive (IC50 0 52 UM) and FcB1 and FcM2 chloroquine-resistant strains of P falciparum (IC50s 0 52 0 8 and 0 49 UM respectively) and reduces parasitemia in a mouse model of P vinckei infection (ED50 18 9 mg/kg per day) decreases LPS-induced increases in TNF-a IL-1B and IL-6 levels and p65 nuclear translocation in RAW 264 7 cells at 5 UM decreases serum levels of IL-10 TNF-a and IL-6 and reduces mortality in a mouse model of LPS-induced endotoxemia inhibits proliferation of various cancer cells (IC50s 2 65-370 ng/ml) induces apoptosis and decreases STAT3 phosphorylation in HSC3 and HSC4 oral cancer cells from 0 1-10 UM and reduces tumor growth in an HSC3 mouse xenograft model at 10 mg/kg per day for 24 days
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The Meso Scale Discovery SARS-CoV-2 S1 RBD N501Y Kit is a research use only immunoassay that detects antibodies generated in response to the SARS-CoV-2 spike protein receptor binding domain containing the N501Y mutation This mutation is present in variants like B 1 1 7 B 1 351 and P 1 The kit contains a plate coated with recombinant SARS-CoV-2 S1 RBD N501Y antigen and all necessary reagents It can quantitatively measure IgG antibodies in serum plasma or other biological fluids in under 3 hours using an electrochemiluminescent detection method The kit has high sensitivity and specificity for assessing immune responses
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The Mesoscale K15662U-2 is a high-performance thermoelectric cooler designed for precision temperature control applications It measures 15mm x 15mm x 3 4mm and provides a maximum heat pumping capacity of 2 5W at 27 C temperature difference This solid-state active cooling device uses the Peltier effect to pump heat and achieves temperature differences up to 70 C With a no load current of 1 4A it can rapidly cool objects when powered by a suitable DC power supply The K15662U-2 thermoelectric cooler is ideal for stabilizing the temperature of laser diodes CCD sensors and other optical components Its compact size makes it suitable for portable and miniaturized devices
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The V-PLEX SARS-CoV-2 Panel 33 IgG Kit from Meso Scale Diagnostics is an immunoassay that uses electrochemiluminescence technology to detect IgG antibodies against 33 antigens from SARS-CoV-2 in human serum and plasma This qualitative assay can aid in identifying individuals with an adaptive immune response to SARS-CoV-2 indicating recent or prior infection The kit includes a 96-well plate coated with SARS-CoV-2 antigens detection antibodies calibrators controls diluent wash buffer read buffer and plate seals Results are analyzed using MSD s imaging systems This assay has high sensitivity and specificity and can be run in approximately 5 hours
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The Mesoscale K15630U-2 is a high-performance thermoelectric cooler with a 30W heat pumping capacity It uses Bismuth Telluride semiconductor elements to transfer heat between ceramic plates when powered Features include a temperature difference over 70 C a 0-4A current range and a compact 30 x 30 x 3 4mm size Weighing 28 grams it offers efficient cooling A heat sink and fan are needed for thermal management Ideal for laser diode cooling medical diagnostics and temperature stabilization
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The Mesoscale K15674U-2 is a high-performance thermoelectric cooler with a maximum heat pumping capacity of 15 5W It consists of an array of 127 thermocouples and can achieve a maximum temperature difference of 70 C The cooler has a footprint of 29 5 x 29 5 mm and operates on a nominal voltage of 3 2V Key features include low electrical resistance high reliability and long service life With robust construction the K15674U-2 is well-suited for stabilizing laser diodes and cooling small objects Its solid-state operation allows quiet vibration-free cooling without any moving parts
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The Meso Scale Discovery V-PLEX Orthopoxvirus Panel 1 IgG Kit is an electrochemiluminescence immunoassay that detects IgG antibodies to vaccinia virus monkeypox virus cowpox virus and ectromelia virus in serum and plasma samples This multiplex assay uses patterned arrays and MSD s proprietary SULFO-TAG labels to provide quantitative results The kit includes a 96-well plate coated with antigens detection antibody wash buffer read buffer calibrator and controls This assay allows high-throughput sensitive and reproducible detection of orthopoxvirus IgG antibodies
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The Mesoscale K15653U-2 is a high-performance thermoelectric cooler with a maximum heat pumping capacity of 15W It contains an array of 127 thermocouples and can achieve a maximum temperature differential of 70 C Some key features include its small footprint of 40 x 40 mm ability to precisely control temperature and solid state operation with no moving parts With a weight of just 85g it s designed for compact portable cooling applications The K15653U-2 requires a controlled DC power source and heat sink for operation
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The Mesoscale K15677U-4 is a 4-channel USB-powered data acquisition device It features 4 analog input channels with 16-bit resolution up to 200 kS/s sampling rate and 10V input range The device connects via USB 2 0 and is compatible with Windows Mac and Linux operating systems Software is included for data logging oscilloscope spectrum analysis and more The compact device is bus-powered so no external power supply is required With its high-speed sampling versatile software and plug-and-play USB connectivity the K15677U-4 is well-suited for a wide range of analog data acquisition applications
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